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Clinical Trials Registries

The AVMA Veterinary Clinical Trials Registry—formerly the AVMA Animal Health Studies Database—helps animal owners and veterinarians find veterinary clinical studies in the U.S. and Canada for their pets and patients. The AVMA is proud to provide this registry to help advance the practice of veterinary medicine and accelerate improvements in animal health care.

Registry Highlights:

  1. Sign in to the new registry with your usual credentials
  2. Access previously submitted studies 
  3. Make edits to ongoing studies
  4. Submit new studies
  5. Manage interested participants
  6. Enter results when studies conclude
  7. Search studies with a variety of criteria and filters

The U.S. Food and Drug Administration has a listing of clinical field studies that are investigating Animal Cells, Tissues, and Cell- and Tissue-Based Products (ACTPs) in veterinary patients. The webpage provides animal owners, veterinarians, researchers, and the public with information on clinical field studies that are being investigated for the use of ACTPs in veterinary patients. Sponsors of ACTPs that are interested in having their clinical trials listed on the FDA’s webpage can contact their FDA project manager

Study Design and Reporting

1. Consolidated Standards of Reporting Trials [CONSORT] The website contains helpful information about abstracts, cluster designs, reporting of harms, herbal interventions, non-inferiority and equivalence studies, trials of non-pharmacologic interventions, and pragmatic trials.

  1. CONSORT Statement: an evidence-based, minimum set of recommendations for reporting randomized trials including a 25-item checklist and a flow diagram.
  2. CONSORT “Explanation and Elaboration” document: explains and illustrates the principles underlying the CONSORT Statement.
  3. Extensions of the CONSORT Statement: give additional guidance for randomized controlled trials (RCTs) with specific designs, data, and interventions.

 Preferred Reporting Items for Systematic Reviews and Meta-Analyses [PRISMA]. Per the website, “PRISMA is an evidence-based minimum set of items for reporting in systematic reviews and meta-analyses” and “focuses on the reporting of reviews evaluating randomized trials….

Reporting guidElines For randomized controLled trials for livEstoCk and food safeTy [REFLECT].  Per the website, REFLECT provides “evidence-based minimum set of items for trials reporting production, health, and food-safety outcomes.

  STARD: The objective of the STARD initiative is to improve the accuracy and completeness of reporting studies of diagnostic accuracy, to allow readers to assess the potential for bias in the study, and to evaluate its generalisability.  Several papers have been published with checklists and flow charts:

Bossuyt PM, et al. 2003. Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. The Lancet. Vol 361.

Bossuyt PM, et al. 2015. An updated list of essential items for reporting diagnostic    accuracy studies. BMJ. 351:5527.

 STrenghtening the Reporting of OBservational studies in Epidemiology [STROBE]:  An international, collaborative initiative of epidemiologists, methodologists, statisticians, researchers, and journal editors involved in the conduct and dissemination of observational studies….  The website includes checklists, publications, a discussion forum, as well as other information.

Veterinary Oncology Clinical Trials:

Thamm DH, Vail DM.  Veterinary oncology clinical trials: design and implementation.    2015. Vet J.


London CA, et al. 2009. Multi-center, placebo-controlled, double-blind, randomized study of oral Toceranib Phosphate (SU11654), a receptor tyrosine kinase inhibitor, for the treatment of dogs with recurrent (either local or distant) mast cell tumor following surgical excision. Cancer Therapy: Clinical.

Burton JH, et al. 2015. Pulse-administered Toceranib Phosphate plus Lomustine for treatment of unresectable mast cell tumors in dogs. JVIM.

The standards of reporting trials in pets (PetSORT): explanation and elaboration.

This publication includes a checklist of information to include when reporting a randomized trial.