Institutional Review Entity (IRE)
IMPORTANT NOTICE:
On May 6, 2024, the US Government released a new Policy for Oversight of Dual Use Research of Concern and Pathogens with Enhanced Pandemic Potential (USG DURC-PEPP Policy). This policy which supersedes previous DURC policies, goes into effect on May 6, 2025. Guidance on implementation of this policy can be found in the USG Implementation Guidance (USG Guidance). CSU’s ICDUR and IRE are working on updating CSU’s DURC Policy and procedures to align with the new USG policy requirements. More information will be posted as it becomes available.
The CSU Institutional Review Entity (IRE) is the local review body charged with oversight and education of life sciences research that falls within the scope of the USG DURC-PEPP Policy. The IRE is responsible for reviewing research with DURC or PEPP potential, as well as working with PIs to assess the risks and benefits of their research and to develop risk mitigation plans where appropriate.
DURC-PEPP at CSU
Although few research activities at CSU would qualify as DURC or PEPP under the definition in the Policy, CSU must comply with the USG Policy for Oversight of DURC and PEPP where applicable. The Office of Research Collaboration & Compliance and the Institutional Review Entity (IRE), with assistance from the Office of Vice President for Research, have developed the CSU’s DURC policy. The effective date of the policy is May 6, 2025.
Resources
CSU DURC-PEPP Training located in SciShield
US Government Policy for Oversight of Dual Use Research of Concern and Pathogens with Enhanced Pandemic Potential (USG DURC-PEPP Policy) – released May 6, 2024
USG Policy Implementation Guidance for research involving DURC and PEPP (USG Guidance)
Questions
Questions about DURC or PEPP can be directed to the IRE Manager