The Pipeline

Translational Healthy aging Endeavor Promoting Interdisciplinary Polyspecies Experimentation Leveraged to Investigate Neurodegeneration and the role of Extracellular vesicles

This study will develop a cells-to-dogs-to-humans research pipeline, investigating the novel hypothesis that extracellular vesicles are drivers of cellular aging and biomarkers of risk for cognitive impairment with age. Specifically, the study will investigate age-related cognitive decline in dogs as a model to inform cognitive decline and late-onset Alzheimer’s disease (AD) in humans. The research pipeline created from this project will accelerate translational aging research at Colorado State University and beyond.

Team Members

Name	Title	College / Department
Karyn Hamilton, RD, PhD, FACSM	Professor, Health and Exercise Science Director, Translational Research on Aging and Chronic Disease Laboratory	College of Health and Human Sciences
Tom LaRocca, PhD	Assistant Professor, Health and Exercise Science Director, Healthspan Biology Lab	College of Health and Human Sciences
Nicole Ehrhart, VMD, MS, Diplomate ACVS	Professor, Clinical Sciences	College of Veterinary Medicine and Molecular Biology
Deana Davalos, PhD	Professor, Psychology Director, Aging Clinic of the Rockies	College of Natural Sciences
Haonan Wang, PhD	Professor, Statistics Chair, Department of Statistics	College of Natural Sciences
Qian Zhang, PhD	Research Scientist and Project Manager, Health and Exercise Science	College of Health and Human Sciences
Devin Wahl	Research Fellow, Health and Exercise Science	College of Health and Human Sciences
Julie Moreno	Assistant Professor, Environmental and Radiological Health Sciences	College of Veterinary Medicine and Biomedical Sciences
Stephanie McGrath	Associate Professor, Clinical Sciences	College of Veterinary Medicine and Biomedical Sciences
Candace Mathiason	Associate Professor, Microbiology, Immunology, and Pathology	College of Veterinary Medicine and Biomedical Sciences
Katriana Popichak	Assistant Professor, Microbiology, Immunology, and Pathology	College of Veterinary Medicine and Biomedical Sciences
Dan Lark	Assistant Professor, Health and Exercise Science; Director, Extracellular Regulation of Metabolism Laboratory	College of Veterinary Medicine and Biomedical Sciences
Kelly Santangelo	Assistant Professor	College of Veterinary Medicine and Biomedical Sciences