The Pipeline

Translational Healthy aging Endeavor Promoting Interdisciplinary Polyspecies Experimentation Leveraged to Investigate Neurodegeneration and the role of Extracellular vesicles

This study will develop a cells-to-dogs-to-humans research pipeline, investigating the novel hypothesis that extracellular vesicles are drivers of cellular aging and biomarkers of risk for cognitive impairment with age. Specifically, the study will investigate age-related cognitive decline in dogs as a model to inform cognitive decline and late-onset Alzheimer’s disease (AD) in humans. The research pipeline created from this project will accelerate translational aging research at Colorado State University and beyond.

Team Members

 NameTitleCollege / Department
Karyn Hamilton, RD, PhD, FACSMProfessor, Health and Exercise Science
Director, Translational Research on Aging and Chronic Disease Laboratory
College of Health and Human Sciences
Tom LaRocca, PhDAssistant Professor, Health and Exercise Science
Director, Healthspan Biology Lab
College of Health and Human Sciences
Nicole Ehrhart, VMD, MS, Diplomate ACVSProfessor, Clinical SciencesCollege of Veterinary Medicine and Molecular Biology
Deana Davalos, PhDProfessor, Psychology
Director, Aging Clinic of the Rockies
College of Natural Sciences
Haonan Wang, PhDProfessor, Statistics
Chair, Department of Statistics
College of Natural Sciences
Qian Zhang, PhDResearch Scientist and Project Manager, Health and Exercise ScienceCollege of Health and Human Sciences
Devin WahlResearch Fellow, Health and Exercise ScienceCollege of Health and Human Sciences
Julie MorenoAssistant Professor, Environmental and Radiological Health SciencesCollege of Veterinary Medicine and Biomedical Sciences
Stephanie McGrathAssociate Professor, Clinical SciencesCollege of Veterinary Medicine and Biomedical Sciences
Candace MathiasonAssociate Professor, Microbiology, Immunology, and PathologyCollege of Veterinary Medicine and Biomedical Sciences
Katriana PopichakAssistant Professor, Microbiology, Immunology, and PathologyCollege of Veterinary Medicine and Biomedical Sciences
Dan LarkAssistant Professor, Health and Exercise Science; Director, Extracellular Regulation of Metabolism LaboratoryCollege of Veterinary Medicine and Biomedical Sciences
Kelly SantangeloAssistant ProfessorCollege of Veterinary Medicine and Biomedical Sciences