The Pipeline

Translational Healthy aging Endeavor Promoting Interdisciplinary Polyspecies Experimentation Leveraged to Investigate Neurodegeneration and the role of Extracellular vesicles

This study will develop a cells-to-dogs-to-humans research pipeline, investigating the novel hypothesis that extracellular vesicles are drivers of cellular aging and biomarkers of risk for cognitive impairment with age. Specifically, the study will investigate age-related cognitive decline in dogs as a model to inform cognitive decline and late-onset Alzheimer’s disease (AD) in humans. The research pipeline created from this project will accelerate translational aging research at Colorado State University and beyond.

Faculty Team Members

Karyn Hamilton, RD, PhD, FACSM
Professor, Health and Exercise Science
Director, Translational Research on Aging and Chronic Disease Laboratory
College of Health and Human Sciences

Tom LaRocca

Tom LaRocca, PhD
Assistant Professor, Health and Exercise Science
Director, Healthspan Biology Lab
College of Health and Human Sciences

Nicole Ehrhart, VMD, MS, Diplomate ACVS
Professor, Surgical Oncology
Department of Clinical Sciences Director, Columbine Health Systems Center for Healthy Aging
Director, Laboratory of Comparative Musculoskeletal Oncology and Traumatology
College of Veterinary Medicine and Molecular Biology

Deana Davalos

Deana Davalos, PhD
Professor, Psychology
Director, Aging Clinic of the Rockies
College of Natural Sciences

Haonan Wang, PhD
Professor, Statistics
Chair, Department of Statistics
College of Natural Sciences

Additional Key Team Members

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Qian Zhang, PhD
Research Scientist and Project Manager, Health and Exercise Science
College of Health and Human Sciences

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Devin Wahl, PhD
Research Fellow, Health and Exercise Science
College of Health and Human Sciences