Mass Spectrometry assays available at ARC-BIO and ARC-MMA
Please contact Corey Broeckling or Claudia Boot for more information.
| Assay | Instrument Type | Sample Type | Analytes | Quantitative | Validation Status | Minutes/ Sample | # Available Instruments | Sample Amount | Sample Amt Units |
|---|---|---|---|---|---|---|---|---|---|
| amino acids | GC-MS | plasma | asparagine, glutamine, glutamate, aspartate, arginine, lysine, histidine, proline, methionine, alanine, glycine, valine, leucine, isoleucine, serine, threonine, cysteine, cystine, phenylalanine, tryptophan, tyrosine | yes | partially | 30 | 4 | 200 | uL |
| branched chain amino acids | GC-MS | plasma | leucine, isoleucine, valine | yes | partially | 30 | 4 | 200 | uL |
| ethyl cabamate | GC-MS | plasma | ethyl carbamate | yes | validated | 16 | 4 | 500 | uL |
| fatty acids | GC-MS | plasma | C14:0, C16:0, C16:1, C18:0, C18:1, C18:2, C18:3, C20 | yes | partially | 17 | 4 | 200 | uL |
| fatty acids | GC-MS | stool | C14:0, C16:0, C16:1, C18:0, C18:1, C18:2, C18:3, C20 | yes | partially | 17 | 4 | 100 | mg |
| Metabolomics | GC-MS | plant | untargeted | relative | partially | 20 | 3 | 100 | mg |
| Metabolomics | GC-MS | plasma | untargeted | relative | partially | 20 | 3 | 100 | uL |
| Metabolomics | GC-MS | stool | untargeted | relative | partially | 20 | 3 | 100 | mg |
| Metabolomics | GC-MS | urine | untargeted | relative | partially | 20 | 3 | 100 | uL |
| Short-chain fatty acids | GC-MS | plasma | acetate, propionate, butyrate | yes | validated | 16 | 4 | 250 | uL |
| Short-chain fatty acids | GC-MS | stool | acetate, propionate, butyrate, isobutyrate, valerate, isovalerate, | yes | partially | 16 | 4 | 30 | mg |
| TCA metabolites | GC-MS | plasma | pyruvate, citrate/isocitrate, cis-aconitate, alpha-ketoglutarate, succinate, fumarate, malate, oxaloaceate | yes | partially | 30 | 4 | 200 | uL |
| Metabolomics | GC-Q-TOF | plant | untargeted | relative | partially | 20 | 1 | 100 | mg |
| Metabolomics | GC-Q-TOF | plasma | untargeted | relative | partially | 20 | 1 | 100 | uL |
| Metabolomics | GC-Q-TOF | stool | untargeted | relative | partially | 20 | 1 | 100 | mg |
| Metabolomics | GC-Q-TOF | urine | untargeted | relative | partially | 20 | 1 | 100 | uL |
| ionomics (26 elements) | ICP-MS | plant | Li, Be, B, Cd, Se, As, Na, P, K, S, Mg, Ca, Al, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Mo, Ba, W, Pb | yes | validated | 6 | 2 | 200 | mg |
| ionomics (26 elements) | ICP-MS | plasma | Li, Be, B, Cd, Se, As, Na, P, K, S, Mg, Ca, Al, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Mo, Ba, W, Pb | yes | partially | 6 | 2 | 200 | uL |
| ionomics (26 elements) | ICP-MS | urine | Li, Be, B, Cd, Se, As, Na, P, K, S, Mg, Ca, Al, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Mo, Ba, W, Pb | yes | partially | 6 | 2 | 200 | uL |
| ionomics speciation | ICP-MS | plant | Se(IV), Se(VI), As(III), As(V), Cr(III), Cr(VI), organic As, Se | yes | unvalidated | 5 | 2 | 200 | mg |
| pigments | LC-PDA | plant | chlorophyll a, chlorophyll b, fucoxanthin, myxoxanthophyll. | yes | unvalidated | 30 | 2 | 100 | mg |
| amino acids | LC-QQQ | plasma | asparagine, glutamine, glutamate, aspartate, arginine, lysine, histidine, proline, methionine, alanine, glycine, valine, leucine, isoleucine, serine, threonine, cysteine, cystine, phenylalanine, tryptophan, tyrosine | yes | partially | 11 | 3 | 200 | uL |
| amino acids | LC-QQQ | plasma | alanine, arginine, asparagine, aspartic acid, glutamic acid, glutamine, glycine, hisitine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, theronine, tryptophan, tyrosine, valine | yes | partially | 34 | 3 | 100 | uL |
| amino acids | LC-QQQ | stool | asparagine, glutamine, glutamate, aspartate, arginine, lysine, histidine, proline, methionine, alanine, glycine, valine, leucine, isoleucine, serine, threonine, cysteine, cystine, phenylalanine, tryptophan, tyrosine | yes | partially | 11 | 3 | 500 | mg |
| antibiotics | LC-QQQ | whole blood | cefepime, flucloxacillin, vancomycin | yes | partially | 11 | 3 | 100 | uL |
| Bile acids | LC-QQQ | stool | serotonin, tryptamine, taurocholic acid (TCA), taurodeoxycholic acid (TDCA), muricholic Acid (5- 3?,6?,7?-trihydroxy-cholan-24-oic acid), glycocholic acid (GCA), 3-oxocholic acid (OCA), ursodeoxycholic acid (UDCA), hyodeoxycholic acid (HDCA), nutriacholic acid (NCA), glycodeoxycholic acid (GDCA), glycochenodeoxycholic acid (GCDCA), cholic acid (CA), 7?-hydroxy-3-oxo-5?-cholanoic acid (OCDCA), cholenic acid (3?-hydroxy-5-cholenoic acid), chenodeoxycholic acid (CDCA), deoxycholic acid (DCA), lithocholic acid (LCA) | yes | partially | 11 | 3 | 500 | mg |
| cannabinoids | LC-QQQ | plant | cannabinol, cannabidiol, delta9-tetrahydrocannabinol, cannabigerol, delta8-tetrahydrocannabinol, cannabidolic acid, tetrahydrocannabivarin, delta9-tetrahydrocannabinolic acid A, cannabigerolic acid, cannabichromene, cannabidivarin | yes | partially | 34 | 3 | 100 | mg |
| cannabinoids | LC-QQQ | plant | cannabinol, cannabidiol, delta9-tetrahydrocannabinol, cannabigerol, delta8-tetrahydrocannabinol, cannabidolic acid, tetrahydrocannabivarin, delta9-tetrahydrocannabinolic acid A, cannabigerolic acid, cannabichromene, cannabidivarin | yes | partially | 27 | 3 | 20 | mg |
| Endocannabinoids | LC-QQQ | plasma | anandamide (AEA), 2-arachidonylglycerol (2-AG) | yes | partially | 20 | 3 | 500 | uL |
| fausdil and hydroxyfausdil | LC-QQQ | plasma | fasudil, hydroxyfasudil | yes | unvalidated | 17 | 3 | 100 | uL |
| karrikins | LC-QQQ | plant | karrikin 1 | relative | unvalidated | 17 | 3 | 100 | mg |
| neurotransmitters | LC-QQQ | plasma | melatonin, serotonin, cortisol | yes | partially | 11 | 3 | 300 | uL |
| Nutrition biomarkers | LC-QQQ | plasma | Pipecolic acid, methyl pipecolate, S-methyl-L-cysteine, S-methyl cysteine sulfoxide, trigonelline, pyridoxal, xanthurenic acid, apigenin, salicylic acid, myo-inositol, salicyluric acid | yes | partially | 40 | 3 | 200 | uL |
| Nutrition biomarkers | LC-QQQ | stool | Pipecolic acid, methyl pipecolate, S-methyl-L-cysteine, S-methyl cysteine sulfoxide, trigonelline, pyridoxal, xanthurenic acid, apigenin, salicylic acid, myo-inositol, salicyluric acid | yes | partially | 40 | 3 | 500 | mg |
| Nutrition biomarkers | LC-QQQ | urine | Pipecolic acid, methyl pipecolate, S-methyl-L-cysteine, S-methyl cysteine sulfoxide, trigonelline, pyridoxal, xanthurenic acid, apigenin, salicylic acid, myo-inositol, salicyluric acid | yes | partially | 40 | 3 | 200 | uL |
| pesticides | LC-QQQ | plant | malathion, imidacloprid, carbaryl, emmamectin, 2,4-dicholorophenoxy acetic acid | yes | partially | 17 | 3 | 100 | mg |
| phytohormones | LC-QQQ | plant | salicylic acid, abscisic acid, jasmonic acid, methyl jasomnante, methyl salicylate | relative | unvalidated | 34 | 3 | 100 | mg |
| Phytohormones | LC-QQQ | plant | salicylic acid, abscisic acid, phaseic acid, trans-zeatin, trans-zeatin riboside, dihydrophaseic acid, indole-3-carboxylic acid, indole-3-acetyl alanine, gibberellic acid-3, indole-3-acetic acid, indole-3-acetonitrile, indole-3-butyric acid, gibberellic acid-4, jasmonic acid,methyl jasmonate, 12-oxo-phytodienoic acid | yes | partially | 20 | 3 | 20 | mg |
| Ractopamine | LC-QQQ | animal tissue | ractopamine | yes | partially | 6.5 | 3 | 20 | mg |
| Redox status | LC-QQQ | whole blood | NR, NAAD, Me4PY, Me2PY, MeNam, AMP, ADP, ATP, NAD, NADH, NADP, NADPH, cADPR, ADPR, NAM, NMN, NAMN | yes | validated | 40 | 3 | 300 | uL |
| sex hormones | LC-QQQ | plasma | estradiol, progesterone, testosterone, dihydrotestosterone (DHT), dehydroepiandrosterone sulfate | yes | partially | 20 | 3 | 500 | uL |
| Sialic acids | LC-QQQ | plant | N-glycolylneuraminic acid (Neu5GC), N-Acetylneuraminic acid (Nue5Ac) | yes | 4 | 3 | 20 | mg | |
| statins | LC-QQQ | urine | hesperetin, pitavastatin, pravastatin | relative | partially | 17 | 3 | 100 | uL |
| tryptophan metabolites | LC-QQQ | stool | 5-hydroxyindole-3-acetic acid (5-HIAA), melatonin, Serotonin, anthranilic acid, indole-3- propionic acid (IPA), 3-methylindole, tryptophan, kynurenic acid, kynurenine, tryptamine, indole-3- acetic acid (IAA) | yes | partially | 11 | 3 | 500 | mg |
| uremic toxins | LC-QQQ | plasma | trimethylamine N-oxide, indoxyl sulfate, p-cresol sulfate | yes | partially | 11 | 3 | 100 | uL |
| Metabolomics | LC-QTOF | plant | untargeted | relative | partially | 20 | 3 | 100 | uL |
| Metabolomics | LC-QTOF | plasma | untargeted | relative | partially | 20 | 3 | 100 | uL |
| Metabolomics | LC-QTOF | stool | untargeted | relative | partially | 20 | 3 | 100 | mg |
| Metabolomics | LC-QTOF | urine | untargeted | relative | partially | 20 | 3 | 100 | uL |
| phenolic acids | LC-QTOF | stool | benzoic acid, 3,4-dihydrophenylacetic acid, phenylacetic acid, 3-phenylpropionic acid, 3-hyrdoxyphenylacetic acid, 4-hydroxy-3-methoxycinnamic acid | relative | partially | 34 | 3 | 100 | mg |
| Metaproteomics | nLC-ORBI | stool | untargeted | no | partially | 90 | 1 | 200 | mg |
| Proteomics | nLC-ORBI | plant | untargeted | no | partially | 90 | 1 | 200 | uL |
| Proteomics | nLC-ORBI | plasma | untargeted | no | partially | 90 | 1 | 200 | uL |
| Proteomics | nLC-ORBI | stool | untargeted | no | partially | 90 | 1 | 200 | mg |
| Proteomics | nLC-ORBI | urine | untargeted | no | partially | 90 | 1 | 200 | uL |
| Protein Crosslinking | nLC-ORBI | protein | structural characterization | no | unvalidated | 90 | 1 | 10 | ug |