Bio-Manufacturing Discussion

As manufacturing operations are increasingly networked, what are the risks that a controller or sample analysis instrument could be attacked and manipulated by outside entities?

The Biomanufacturing discussion will take place Tuesday, April 6 from 4-6 p.m. on Zoom.

Register in advance for this discussion.

Moderator:

Ken Reardon

Ken Reardon, Ph.D.

Professor & Associate Department Head
Chemical & Biological Engineering

Colorado State University

Dr. Reardon is Professor and Jud and Pat Harper Chair of Chemical and Biological Engineering, and holds joint appointments in several other science and engineering programs at CSU, including Cell and Molecular Biology and Biomedical Engineering.  His research combines bioreactor analysis, systems biology, and applied microbiology and microbial ecology. His group’s current projects involve the analysis and engineering of bacteria and algae for the production of biofuels and other chemicals, biosensors, and the application of proteomics to microbiome analysis.  He is also interested in the interconnected challenges of food, energy, and water production.  Dr. Reardon is also the founder and Chief Technology Officer of OptiEnz Sensors, which is based on research from his laboratory.  Dr. Reardon received the Faculty Excellence Award from the College of Engineering at CSU in 2009.

Speakers:

Corey Hudson

Corey M. Hudson, Ph.D.

Manager Computational Biology and Biophysics, Sandia National Laboratories

Corey Hudson is a manager in Computational Biology and Biophysics at Sandia National Laboratories. He has a Ph.D. in Informatics from the University of Missouri. Dr. Hudson has been at Sandia since 2013 and has led teams in cybersecurity, machine learning, synthetic biology and genomics. His principal work has been in modeling and simulating cybersecurity risks in realistic and large-scale genomic systems and highly automated synthetic biology facilities.

Presentation title: Digital Biosecurity

Charles Fracchia

Charles Fracchia

CEO of BioBright & VP of Data at Dotmatics

Charles is the founder of BioBright, a Boston-based company that automates the secure data collection and analysis from laboratory and biomanufacturing environments. BioBright was originally funded by DARPA to create DarwinSync a scalable and end-to-end encrypted data collection and analytics system. In June 2020, BioBright was acquired by Dotmatics, and in March 2021 merged with Insightful Science to create an end-to-end cloud and data-centric portfolio from computer-aided design to secure data aggregation and analytics. BioBright continues to operate as a wholly owned subsidiary based in Boston, MA.

Charles received his graduate education between the MIT Media Lab and Harvard Medical School and obtained his bachelor’s degree from Imperial College London. Charles gained critical experience from his work at IBM Research and Ginkgo Bioworks where he was respectively the first synthetic biologist and first full-time person outside of the founding team. He has received a number of awards including MIT Technology Review’s 35 under 35, IBM PhD fellowships and the Extraordinary Minds fellowship.

Presentation Title: Digital Biosecurity: the looming threat to the bioeconomy

The advent of digitization in the life sciences and pharmaceutical sectors present an unprecedented opportunity to leverage data-driven techniques to speed up R&D processes. However, with digitization also come new attack vectors and updated threat models that must be carefully considered in order to avoid introducing vulnerabilities that threaten the whole process or workflow. In this talk we will outline some of the threats that can arise from vulnerable tools in the biomanufacturing chain, and provide a set of questions and framework to help practitioners think and assess digital biosecurity issues.

Lucas Hartsough

Lucas Hartsough, Ph.D.

Senior Design Engineer, Ginkgo Bioworks, Inc.

As a member of Ginkgo’s Design Team, Lucas uses computational biology and machine learning to design DNA. He is also a member of Ginkgo’s FELIX Team, an IARPA-funded project focused on building computational tools to detect hallmarks of genetic engineering in sequencing samples. He received his PhD in Bioengineering from Rice University in 2018 and has been with Ginkgo ever since.

Presentation title: Biosecurity at Scale